Vol. 28, No. 3, 2006 (October)
	Content

MOLECULAR AND CLINICAL CONDITIONS ASSOCIATED WITH VENOUS THROMBOEMBOLISM IN ONCOLOGICAL PATIENTS

P. Di Micco^{1, 2,} *, M. Amitrano³, A. Niglio⁴, A. Fontanella¹

¹Division of Internal Medicine, Buonconsiglio Fatebenefratelli Hospital of Naples, Naples, Italy
²Department of Biochemistry and Medical Biotechnology and CEINGE SCARL, Federico II University of Naples, Naples, Italy
³Division of Angiology, A.O.R.N. G. Moscati, Avellino, Italy
⁴IV Division of Internal Medicine, Second University of Naples, Naples, Italy

Abstract. The association between cancer and thrombophilia has been known since 1865 since Trousseau described it. However in the last three decades an increased interest has been raised on this issue related to several molecular and condition that are involved in the daily management of oncological patients. This brief review has been focused on molecular conditions underlying cancer acquired thrombophilia then to further clinical aspects inducing thrombophilia in oncological patients such as surgery, chemotherapy, concomitant medical illness and inherited thrombophilia.

Key Words: cancer, thrombophilia, hypercoagulable state, inherited thrombophilia, chemotherapy

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