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Medline

PubMed, a service of the National Library of Medicine

World Oncology Network

R.E.Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology



Vol. 24, No. 2, 2002 (June)

Content

DELETION IN dbl DOMAIN OF bcr/abl GENE IN LEUKEMIA PATIENTS WITH Ph' CHROMOSOME

 

M.V. Dybkov, G.D. Telegeev, A.N. Dubrovskaya, S.S. Maliuta

Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine

Abstract. In some leukemia patients with Ph' chromosome the presence of deletions in the dbl domain of hybrid bcr/abl gene was shown. The possible influence of such genetic alterations on peculiarities of disease course is discussed.

Key Words: deletion, bcr/abl gene, dbl domain, Ph' chromosome, leukaemia.

Language:  English

[full text]




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